Re: Another Odd Question. . .
I co-wrote and drew a comic which featured one humungus story arc over several issues with a two/four page vignette per issue with a world-connected but otherwise stand-alone story. None of the central characters, other than those who were unavoidable (given the nature of the society we depicted), was featured.
In another comic I did solo I continued the idea and had a short story told by one of the central characters. It was usually a sort of Future Shocks.