Re: "Personal" question(s) to John Jarrold
Yes, it boils down to the fact that no agent or publisher will take you on unless they LOVE your writing, personally and professionally, and they will not view a dyslexic or anyone else in a different manner from usual. If the book ain't WONDERFUL (and produced to a totally professional standard), it won't be taken on.
One of the novelists I worked with for a number of years in publishing is dyslexic. They delivered probably the best, cleanest typescripts I've seen.
I'll say it again: if the words aren't right, nothing else matters.